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Redesign of a rapid, low-cost HPV typing assay to support risk …
WebStandard Fire Assay or Screen Fire Assay? Application of the Overall Measurement Error Approach to Choose the Most Appropriate Method In cases where coarse gold is present … Webpositivity between ScreenFire and prior PCR testing was very high for each of the channels. When we simulated intended use, that is, a hierarchical result in order of clinical importance of the type groups (HPV16 > 18/45 > 31/33/35/52/58 > 39/ 51/56/59/68), the weighted kappa for ScreenFire vs PCR was 0.90 (95% CI: 0.86-0.93). WebThe ScreenFire assay is mobile, relatively simple, rapid (results within 20-60 minutes), and agrees well with reference testing particularly for the HPV types of greatest carcinogenic risk. If confirmed, ScreenFire or similar isothermal amplification assays could be useful as part of risk-based screening and management. tally aws pricing